Description
Humana Press Inc. Telomerase Inhibition Strategies And Protocols by Lucy Andrews
This volume presents a compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition. The techniques described provide the researcher with a diverse and comprehensive set of tools for the study of telomerase inhibition. The volume is aimed at biochemists, molecular biologists, cancer researchers, and geneticists._x000D_ _x000D_
Contents:_x000D_
_x000D_
Preface_x000D_
Contributors_x000D_
_x000D_
_x000D_
1. Methods of Telomerase Inhibition_x000D_
Lucy G. Andrews and Trygve O. Tollefsbol_x000D_
_x000D_
2. Telomerase Inhibition by Synthetic Nucleic Acids and_x000D_
Chemosensitization in Human Bladder Cancer Cell Lines_x000D_
Kai Kraemer, Susanne Fuessel, and Axel Meye_x000D_
_x000D_
3. hTERT Knockdown in Human Embryonic Kidney Cells Using_x000D_
Double-Stranded RNA_x000D_
Serene R. Lai, Lucy G. Andrews, and Trygve O. Tollefsbol_x000D_
_x000D_
4. RNA Interference Using a Plasmid Construct Expressing Short Hairpin_x000D_
RNA_x000D_
Serene R. Lai, Lucy G. Andrews, and Trygve O. Tollefsbol_x000D_
_x000D_
5. Retrovirus-mediated RNA Interference: Targeting hTERT Through Stable_x000D_
Expression of Short Hairpin RNA_x000D_
Amanda P. Cunningham, Lucy G. Andrews, and Trygve O. Tollefsbol_x000D_
_x000D_
6. Telomerase Inhibition and Telomere Targeting in Hematopoietic Cell_x000D_
Lines with Small Non-Nucleosidic Synthetic Compounds (BIBR1532)_x000D_
Hesham El Daly and Uwe M. Martens_x000D_
_x000D_
7. Uses of Telomerase Peptides in Anti-tumor Immune Therapy_x000D_
He Li, Indzi Katik, and Jun-Ping Liu_x000D_
_x000D_
8. Establishing Cell-based Reporter Systems for the Analysis of hTERT_x000D_
expression_x000D_
Yi-Yuan Huang, Jing-Wen Shih, and Jing-Jer Lin_x000D_
_x000D_
9. Telomerase RNA Inhibition Using Antisense Oligonucleotide Against_x000D_
Human Telomerase RNA Linked to a 2', 5'-Oligoadenylate (2-5A)_x000D_
Yasuko Kondo and Seji Kondo_x000D_
_x000D_
10. Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA_x000D_
Interference_x000D_
Shang Li, Mehdi Nosrati, and Mohammed Kashani-Sabet_x000D_
_x000D_
11. Evaluation of Tankyrase Inhibition in Whole Cells_x000D_
Tomohazu Ohishi, Takashi Tsuruo, and Hiroyuki Seimiya_x000D_
_x000D_
12. Inhibition of Telomerase by Targeting MAP Kinase Signaling_x000D_
Dakang Xu, He Li, and Jun-Ping Li_x000D_
_x000D_
13. Screening of Telomerase Inhibitors_x000D_
Elke Kleideiter, Kamilla Piotrowska, and Ulrich Klotz_x000D_
_x000D_
14. Telomerase Inhibition Combined with Other Chemotherapeutic Reagents_x000D_
to Enhance Anti-Cancer Effect_x000D_
Tetsuzo Tauchi, Junko H. Ohyashiki,and Kazuma Ohyashiki_x000D_