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Taylor & Francis Inc The Chemical Components of Tobacco and Tobacco Smoke 2013 Edition by Alan Rodgman, Thomas A. Perfetti
Authored by two longtime researchers in tobacco science, The Chemical Components of Tobacco and Tobacco Smoke, Second Edition chronicles the progress made from late 2008 through 2011 by scientists in the field of tobacco science. The book examines the isolation and characterization of each component. It explores developments in pertinent analytical technology and results of experimental studies on biological activity, toxicity, and tumorigenicity, including the inhibition of adverse biological activity of one specific tobacco smoke component by another tobacco smoke component. Adding to the progress reported in the First Edition, the comprehensive Second Edition provides nearly 7,000 references on almost 9,600 components. The authors discuss the controversies over the extrapolation of the biological effect of a specific component administered individually by one route versus its biological effect when the component is in a highly complex mixture and is administered by a different route. They also cite studies in which cigarette design technologies were developed to control the per-cigarette mainstream smoke yield of Federal Trade Commission-defined tar and one or more specific tobacco smoke components of concern.New in the Second Edition:Approximately 1,000 newly reported components have been inserted and several dozen duplicates have been deleted from various tables and from the Alphabetical IndexImproved and sharper chemical structuresInsertion of new pertinent references for the components in each of the major chapter tables devoted to a particular functional componentUpdated Index organized by the CAS Registry Number listing of the componentsUpdated discussions in the Introduction and at the beginning of each chapterA searchable companion CD-ROM containing the 350-page alphabetical Component IndexAuthors Alan Rodgman and Thomas A. Perfetti were jointly awarded the 2010 CORESTA (Cooperative Centre for Scientific Research Relative to Tobacco) Prize for their extensive work on documenting the vast literature on the chemical composition of tobacco and tobacco smoke in their original edition. Table of contents : - HydrocarbonsAlkanesAlkenes and AlkynesAlicyclic HydrocarbonsMonocyclic Aromatic HydrocarbonsPolycyclic Aromatic HydrocarbonsSummaryAlcohols and PhytosterolsAlcoholsPhytosterolsAldehydes and KetonesAssertion of Aldehydes and Ketones as Ciliastatic Tobacco Smoke ComponentsCiliastasis Studies with Cigarette Smoke Condensate FractionsCiliastasis Studies with Individual Cigarette Mainstream Smoke ComponentsNose Inhalation of Environmental Tobacco Smoke vs. Mouth Inhalation of Mainstream SmokeCarboxylic AcidsCarboxylic AcidsAmino Acids and Related CompoundsEstersLactonesAnhydridesCarbohydrates and Their DerivativesPhenols and QuinonesPhenolsQuinonesEthersOverall Summary of Oxygen-Containing Components of Tobacco and/or Smoke: Chapters 2 through 10NitrilesAcyclic AminesAmidesImidesN-NitrosaminesVolatile NNAsNonvolatile NNAsTobacco-Specific NNAsN-Nitrosamino AcidsTobacco-Specific NNAs: An Exception among the Major MSS ToxicantsDirect Transfer of TSNAs from Tobacco vs. Their Formation during the Smoking ProcessInfrequently Studied Tobacco and/or Smoke Secondary Amines and Their N-NitroaminesFlue Curing and TSNAsNitroalkanes, Nitroarenes, and NitrophenolsNitrogen Heterocyclic ComponentsMonocyclic Four and Five-Membered N-Containing Ring CompoundsMonocyclic Six-Membered N-Containing Ring CompoundsLactamsOxazoles and OxazinesAza-ArenesN-Heterocyclic AminesMiscellaneous ComponentsSulfur-Containing ComponentsHalogenated ComponentsFixed and Variable GasesAnalytical MethodsMetallic and Nonmetallic Elements, Isotopes, Ions, and SaltsElements, Isotopes, and Ions in PlantsMethods for the Detection and Identification of Metals, Ions, and Isotopes in Tobacco and Tobacco SmokeThe Transference of Elements, Isotopes, and Ions from Tobacco to Tobacco SmokeSummaryPesticides and Growth RegulatorsSynthetic Pesticides and Plant Growth Regulator Residues on TobaccoNaturally Occurring Plant Growth Regulators and Pesticides in TobaccoTransfer Rates of Pesticides and Plant Growth Regulators to MSSDecomposition Products of Agrochemicals in MSSMethods for Analyses of Pesticides and Plant Growth RegulatorsResidues of Synthetic Pesticides and Plant Growth Regulators Identified in Tobacco and Tobacco SmokeGenes, Nucleotides, and EnzymesGeneral Discussion of GeneticsTobacco GeneticsGenes, Nucleotides, and Enzymes Identified in TobaccoAcknowledgmentsHoffmann AnalytesTobacco and/or Tobacco Smoke Components Used as Tobacco IngredientsAcknowledgmentPyrolysisIndividual Tobacco TypesExtracts from TobaccoIndividual Tobacco ComponentsTobacco AdditivesCigarette Construction Materials (Paper, Adhesives, etc.)Flavoring IngredientsCarcinogens, Tumorigens, and Mutagens vs. Anticarcinogens, Inhibitors, and AntimutagensCarcinogens, Tumorigens, and MutagensAnticarcinogens, Inhibitors, and AntimutagensSummaryFree RadicalsIntroductionAnalytical Methods for Determination of Free RadicalsFree Radicals in Tobacco SmokeHistorical Review of Free-Radical Research on Cigarette SmokeProposed Mechanism for the Generation of Free Radicals in MSSSummaryBibliographyAlphabetical Component IndexSequence of CAS Registry Numbers