Description
Taylor & Francis The Essential Stratum Corneum 2002 Edition by Ronald Marks, Jean-Luc Leveque, Rainer Voegeli
Dermatological conditions are explored fully in the medical literature, but this text will become the standard reference on the topmost layer of the skin. It distinguishes itself by its scholarship, its comprehensive treatment of all aspects of this specific subject, its accessibility and especially its focus. The editors have brought together international researchers to give an evidence-based presentation of the stratum corneum. From consumer demands and dandruff to aging and water absorption, these experts profile everything about this part of the skin, and they do so in a highly detailed but straightforward way. Dermatologists will find The Essential Stratum Corneum to be the standard text on the subject. Table of contents :- Ultrastructural aspects of stratum corneum. Formation and function of the stratum corneum. Update on desquamation: First evidence for the presence of endoglycosidase activity in the human stratum corneum. Purification and characterization of heparanase 1 (Hpa1). Crossing the barrier. Understanding and measuring the optics that drive visual perception of skin appearance. Environmental threats to the stratum corneum. The scale of the problem. Lipid organization and barrier function. Corneodesmosomal proteins are proteolysed in vitro by both SCTE and SCCE, two proteases which are thought to be involved in desquamation. Calmodulin like skin protein (CLSP): A new marker of keratinocyte differentiation. Association of hsp27 with epidermal structural proteins and its expression in keratinization disorders. The single gel-phase model and the membrane folding model for skin barrier structure, function and formation. Comparison of cutaneous bioavailability of cosmetic formulations containing caffeine or alpha-tocopherol applied on human skin models or human skin ex vivo at finite doses. Structure of multi-phasic dermal formulations and the influence of the structure and of vehicle evaporation on transdermal permeation. Transdermal iontophoresis of leuprolide in vitro under constant voltage and constant current conditions: Physicochemical modeling and the effect of adjuvants. Quantification of vitamin E-acetate (cosmetic formulations) in the stratum corneum of an in-vitro model by tape stripping, UV-spectroscopy and HPLC-method. The effect of extraction and NMF treatment on the water handling capability of stratum corneum as measured by TEWL and MAT. Electrical impedance. A method to evaluate the ability to betaine to reduce the skin irritating effects of detergents. Electrical capacitance measurement of the stratum corneum hydration: Comparison with the dermopharmacokinetics of the active moiety. Evaluation of surfactant effects on stratum corneum using squamometry, transepidermal water loss measurements and the sorption-desorption test. Influence of in vivo iontophoresis on the skin barrier and percutaneous penetration. Epidermal in vivo and in vitro studies by attenuated total reflection spectroscopy using a novel flexible mid-infrared fiber probe. Non-invasive sampling of glucose by reverse electroporation of human skin. FOITS - Corneometry influenced by experimental side conditions. Morphological alterations in the stratum corneum of winter xerosis skin. Non homogeneous distribution of topically applied compounds. Normalization of inflammation and humidity in SLS perturbed skin in vivo by gel state phosphatidyicholine. Sensitive skin: cosmetic and dermatological treatment. One more plain (plane) look into the stratum corneum. Penetration enhancement by interaction of the human stratum corneum with externally applied lipids and terpenes. Irritant and allergic contract dermatitis: beneficial corneotherapeutic effects of skin-tolerance tested moisturizing creams. Dandruff is characterized by decreased levels of intercellular lipids in scalp stratum corneum. Mechanical properties of aging skin - Stratum corneum vs dermal changes. FTIR mapping: A tool for spatially resolved characterization of stratum corneum. In vitro systems to characterize dermal permeation and penetration. Changes in skin constitution and consumers' demands in the last decades. Seasonal changes in skin biophysical properties in healthy Caucasian women. Influence of phloretin and 6-ketocholestanol on the penetration of 5-aminolevullnic acid through porcine skin. A decrease of b-glucocerebrosidase activity induced by UVB causes a skin barrier abnormality. Effect of menthol. A chiral permeation enhancer, on ibuprofen skin permeation. Non-invasive evaluation on cornified envelope maturation. Application of hyperosmolar glucose on injured skin: Skin bioengineering evaluation during epidermal barrier repair. Organization of the intercellular spaces of human palmo-plantar stratum corneum. Rapid infrared spectrometric quantitation of stratum corneum lipid content. A new method for contactiess in vivo quantitative measurement of stratum corneum gloss attributes. Influence of natural ingredients. The combination of neutron scattering techniques for the study of hydration of porcine stratum corneum. Permeation and sorption studies of water transport in stratum corneum. Expression analysis of stratum corneum chymotryptic enzyme (SCCE) and its precursor at the surface of human epidermis, using affinity-purified anti-peptide antibodies. An in vivo method to study stratum corneum-surfactant interactions. The effect of change in epidermal calcium gradient on stratum corneum lipid and epidermal differentiation. Structure determination of human epidermal glucosylceramides. Localization of titanium dioxide microparticles in the horny layer. Ultrastructural effects of some topical corticosterioids upon the epidermal layers. Comparison of the barrier properties of artificial skin constructs and stratum corneum for 5-aminolevullinic acid and its n-butyl ester. Lateral drug infusion in comparison of an artificial skin construct and stratum corneum for 5-aminolevulinic acid and its n-buytl este. Comparison of commercial hydrocortisone formulations with regard to their permeation behaviour through excised stratum corneum. Transepidermal water loss (TEWL) does not correlate with skin permeability in vitro. A random walk model of stratum corneum diffusion. Characterization of skin surface: comparison of SIA(r) and PRIMOS(r) methods. TEWL and stratum corneum hydration changes caused by prolonged contact with a new TEWL measurement head. How cosmetics interact with the stratum corneum. Evaluation of a spectrophotometric, in situ determination as a stand-alone method for percutaneous bioavailability studies. Visual features of healthy skin - A comparison of the evaluation on volunteers and high resolution digital images. Recent investigations on the reservoir function of the stratum corneum. Stratum corneum lipid composition as a predictive tool for permeability? Improved understanding of skin elasticity by modelling in vivo mechanical tests. Strategies for improving skin moisture. Proliferation and survival of cultured melanoma cells following exposure to Dead Sea halobacteria homogenate and Percutaneous Absorption. Bioengineering Techniques. Clinical and Cosmetic Considerations.