Description
Taylor & Francis The Human Complement System in Health and Disease 1998 Edition by John E. Volanakis
This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Diseasedescribes the molecular architecture of the complement system details the structure of complement genes discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway elucidates the regulation of complement gene expression and the structure and function of bioactive peptides explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria and more! Table of contents : - Introduction and Historical Notes, Michael M. Frank Molecular Architecture Overview of the Complement System, John E. VolanakisClq and Mannose-Binding Lectin, Kenneth B. M. ReidComplement Enzymes, John E. Volanakis and Gerard J. ArlaudThe Chemistry and Biology of C3, C4, and C5, John D. Lambris, Arvind Sahu, and Rick A. WetselProteins of the Membrane Attack Complex, Mnason E. Plumb and James M. SodetzRegulatory Proteins of Complement, M. Kathryn Liszewski and John P. AtkinsonComplement Receptors, Joseph M. Ahearn and Ariella M. RosengardPhylogeny of the Complement System, Masaru NonakaRegulation of Complement Protein Gene Expression, Harvey R. Colten and Gerard GarnierBiology Characterization of Complement Anaphylatoxins and Their Biological Responses, Julia A. Ember, Mark A. Jagels, and Tony E. HugliComplement-Mediated Phagocytosis, Melvin BergerCellular Responses to the Membrane Attack Complex, Carolyn MoldRegulation by Complement of Acquired Immunity, Michael C. Carroll and Douglas T. FearonEndothelial Cell Responses to Complement Activation, Soheyla Saadi and Jeffrey L. PlattThe Complement System in Reproduction, Teresa J. OglesbyBacteria and Complement, Franz Petry and Michael LoosComplement and Viruses, Neil R. CooperComplement and Disease Complement Deficiencies and Infection, Peter DensenProcessing and Clearance of Immune Complexes by Complement and the Role of Complement in Immune Complex Diseases, Kevin A. Davies and Mark J. WalportC1 Inhibitor Gene and Hereditary Angioedema, Alvin E. Davis IIIParoxysmal Nocturnal Hemoglobinuria and Complement, Wendell F. Rosse Complement in Central Nervous System Disorders, Moon L. Shin, Horea Rus, and Florin NiculescuDevelopment of Clinically Useful Agents to Control Complement-Mediated Tissue Damage, Eric Wagner and Michael M. FrankAutoimmune Hemolytic Anemia, Alan D. SchreiberComplement and Glomerular Diseases, Clark WestRole of Complement in Diseased and Normal Human Skin, Kim B. Yancey and Thomas J. LawleyComplement and Neuromuscular Diseases, Milan Basta and Marinos C. Dalakas