Description
Taylor & Francis The Myelodysplastic Syndromes Pathobiology and Clinical Management 2002 Edition by John Bennett
This reference provides a comprehensive overview of the latest research detailing the etiology, epidemiology, treatment, and detection of myelodysplastic syndromes (MDS)-identifying effective therapeutic regimens, adverse environmental and genetic factors, and efficient modalities of supportive care that improve patient survival and enhance quality of life.Contains recent amendments to MDS classification criteria by the World Health Organization!The Myelodysplastic Syndromes discussesimmunological abnormalities and inflammatory diseases associated with MDS the development of therapy-related MDS auto and allo bone marrow transplantation the formation of apoptotic signals pharmacologic strategies for multidrug resistance in MDS patients the biological mechanisms of childhood MDSPresenting current guidelines to predict disease prognosis, The Myelodysplastic Syndromes is a detailed and timely guide for oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists, molecular biologists, and medical school students in these disciplines. Table of contents :- Myelodysplastic Syndromes: Historical Aspects and ClassificationJohn T. Phelan II, Peter A. Kouides, and John M. BennettEpidemiology of the Myelodysplastic SyndromesTerry J. HamblinCausative Agents in the Etiology of the Myelodysplastic Syndromes and the Acute Myeloid LeukemiasMartyn T. Smith, Martha S. Linet, and Gareth J. MorganImmunology Aspects of the Myelodysplastic SyndromesTerry J. HamblinThe Cytogenetics and Molecular Biology of the Myelodysplastic SyndromesHarold J. Olney and Michelle M. Le BeauHypocellular Myelodysplastic Syndromes and Hypocellular Acute Myeloid Leukemias: Relationship to Aplastic AnemiaMasao Tomonaga and Kazuhiro NagaiThe Syndrome of Therapy-Related Myelodysplasia and Myeloid LeukemiaLucy A. Godley and Richard A. Larson The Role of Apoptosis in the Myelodysplastic SyndromesYataro YoshidaApplication of Single and Multiple Prognostic Factors in the Assessment of Patients with the Myelodysplastic SyndromesCarlo Aul, Aristoteles Giagounidis, and Ulrich GermingResponse Criteria for Myelodysplastic SyndromesBruce D. ChesonMechanisms of Drug Resistance in Myelodysplastic Syndromes and Acute Myeloid LeukemiaRobert B. Geller and Alan F. ListMyelodysplastic Syndrome and Juvenile Myelomonocytic Leukemia in ChildrenHenrik Hasle and Charlotte NiemeyerTreatment of Anemia in Myelodysplastic SyndromesEva Hellstroem-Lindberg and David T. BowenImmune Mediation of Pancyctopenia in Myelodysplastic Syndromes: Pathophysiology and TreatmentNeal S. Young and A. John BarrettNew Investigational Strategies in Patients with Myelodysplastic SyndromesGuillermo Garcia-Manero and Hagop M. KantarjianIntensive Chemotherapy, Including Autologous and Stem Cell Transplantation in the Myelodysplastic SyndromesTheo M. de Witte and Margriet OosterveldAllogeneic-Bone Marrow Transplantation in the Myelodysplastic SyndromesJeanne E. AndersonTherapeutic Strategies in the Care of Patients with Myelodysplastic SyndromesDragana Milojkovic and Ghulam J. MuftiIndex