Description
CAMBRIDGE Toxoplasmosis A Comprehensive Clinical Guide by David H. M. Joynson, Tim G. Wreghitt
This authoritative and comprehensive account looks at the re-emergence of toxoplasmosis as a significant and potentially fatal infection. A team of acknowledged international experts review the latest diagnostic techniques, and the management of infection in pregnant women, neonates, the eye, transplant and other immunosuppressed patients and those with AIDS. The contentious issue of the role of screening during pregnancy and in the new-born is covered in depth. The introductory chapters on biology, immunology and epidemiology of the infection provide essential background to understanding the clinical disease. The full range of treatment strategies are presented in an easily accessible form. The natural history and life cycle of the causative organism, Toxoplasma gondii, provide a fascinating insight into one of the most successful parasites on earth. Although the burden of this disease varies greatly from country to country, it remains a global public health problem which affects about one billion individuals.
Preface; Historical perspective; 1. Biology Eskild Petersen and J. P. Dubey; 2. Immunology of toxoplasma infection Christopher A. Hunter and Gabrielle Reichman; 3. Epidemiology Susan M. Hall, Michael Ryan and David Buxton; 4. Infection in the immunocompetent Darrel O. Ho-Yen; 5. Infections in HIV positive patients Peter Mariuz and Roy T. Steigbigel; 6. Infection in other immunosuppressed patients Tim G. Wreghitt and David H. M. Joynson; 7. Maternal and fetal infection Philippe Thulliez; 8. Prenatal screening Ruth Gilbert and Catherine S. Peckham; 9. Newborn screening Roger Eaton, George F. Grady and Ho-Wen Hsu; 10. Infections in neonates and infants Jacques Couvreur; 11. Ocular infection Gordon N. Dutton; 12. Laboratory diagnosis of infection David H. M. Joynson and Edward C. Guy; 13. Antitoxoplasma chemotherapy Robert E. McCabe; 14. Vaccines James L. Fishback and Jack Frenkel; Appendices: Appendix 1. Suggested treatment protocols; Appendix 2. Management of toxoplasma infection in pregnancy; Appendix 3. Hygiene measures to prevent infection; Appendix 4. Classification system and case definitions; Index.