Description
Picsie Books The Lean Games Book by John Bicheno
Games have been an integral part of Lean Education and Training ever since Hewlett Packard made their 'Stockless Production' video in 1982. Over two decades John Bicheno had been developing and refining games for all aspects of Lean and Operations Management. These have been assembled together to produce a compendium that will be useful to Lean and Operations trainers everywhere. Although one cannot learn about Lean exclusively from playing games, games do allow quick experiential learning that reading about Lean, or listening to a lecture, cannot convey. Games allow players not only to learn about the interaction of particular Lean tools, but also to develop the richness of discussion, participation, and decision making that are essential requirements for successful Lean implementation. This collection covers a wide field including waste reduction, 5S, scheduling, layout, TPM, design, quality, and changeover, as well as an appreciation of the effects of variation and utilization. Some specific and perhaps lesser-known concepts such as Drum Buffer Rope, CONWIP and Bucket Brigade line balancing are also included. All the games presented here have been thoroughly tested and played in plant, academic, and workshop settings._x000D_ Table of contents :- _x000D_
Molecular Actions of Steroid Hormones.- Molecular Actions of Steroid Hormones.- Steroid Receptor Activation: The Glucocorticoid Receptor as a Model System.- "Defective" Receptors in Steroid-Resistant Conditions May Be Proteolytic Artifacts.- Characteristics and Specificity of the Glucocorticoid "Carrier" of Rat Liver Plasma Membrane.- Glucocorticoid Functions and Resistance.- Mechanisms of Glucocorticoid Hormone Action.- Glucocorticoid Physiology, Pharmacology and Stress.- Cortisol Resistance in Man.- Glucocorticoid Receptors and Glucocorticoid Resistance in Human Leukemia in Vivo and in Vitro.- The New World Primates as Animal Models of Glucocorticoid Resistance.- Mineralocorticoid Action and Resistance.- Aldosterone Receptors.- Models of Aldosterone Action on Sodium Transport: Emerging Concepts.- Pseudohypoaldosteronism: A Review and Report of Two New Cases.- Animal Models of Mineralocorticoid Resistance.- Androgen Action and Resistance.- Differential Regulation of Specific Gene Expression in Mouse Kidney by Androgens and Antiandrogens.- Androgen Receptors in Normal and Abnormal Male Sexual Differentiation.- Androgen Resistance in Man.- Animal Models of Androgen Insensitivity.- High Plasma Steroid Levels in the Squirrel Monkey: Deficient Receptors or Metabolism?.- Female Sex Steroids: New Aspects on the Mechanism of Action and Resistance States.- Progesterone Receptor Interaction in the 5'-Flanking Regulatory Region of the Ovalbumin Gene.- An Endogenous Ligand for Type II Binding Sites in Normal and Neoplastic Tissues.- Progesterone Resistance.- Estrogen and Antiestrogen Resistance in Human Breast Cancer Cell Lines.- Altered Estrogen Action in the Senescent Rat Uterus: A Model for Steroid Resistance During Aging.- Vitamin D Functions, Cellular Actions and Resistant States.- The Metabolism and Functions of Vitamin D.- 1,25-Dihydroxyvitamin D3 Receptors: Altered Functional Domains Are Associated with Cellular Resistance to Vitamin D3.- Clinical Features of Hereditary Resistance to 1,25-Dihydroxyvitamin D (Hereditary Hypocalcemic Vitamin D Resistant Rickets Type II).- The Molecular Basis for Resistance to 1,25-Dihydroxyvitamin D: Studies in Cells Cultured from Patients with Hereditary Hypocalcemic 1,25(OH)2D3 Resistant Rickets.- The Common Marmoset as an Animal Model for Vitamin D-dependent Rickets, Type II._x000D_