Description
Springer Can a Virus Cause Schizophrenia? Facts and Hypotheses 1st Editon 2012 Softbound by Bradley D. Pearce
1 Introduction and History.- 1.1 A brief history of the viral hypothesis.- 2 Fundamentals of Viral Infections and Immune Responses in Humans.- 2.1 A primer on general virology.- 2.2 Immune response to viral infections.- 2.3 Persistent viral infections.- 3 Encephalitis and Schizophrenia.- 3.1 Viruses and schizophrenia: a plurality of theories.- 3.2 Psychosis in viral encephalitis.- 3.3 The validity gap for the encephalitis connection.- 3.4 Bona diseases virus.- 3.5 Viruses in other psychiatric diseases.- 4 Epidemiological Evidence.- 4.1 Epidemiological studies of the viral hypothesis.- 4.2 Seroepidemiological studies.- 4.3 Immune alterations in schizophrenia.- 5 The Role of Viral Infections During Neurodevelopment.- 5.1 Brain development.- 5.2 Immunology of the maternal-fetal unit.- 5.3 The viral-developmental hypothesis.- 5.4 Epidemiological studies of perinatal infections in adult schizophrenia.- 6 Model and Mechanisms.- 6.1 Specific models.- 6.2 A history lesson from oncology concerning the viral hypothesis.- 6.3 What a viral etiology of schizophrenia does not mean.- 6.4 Conclusion.